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CFH, C3 and ARMS2 Are Significant Risk Loci for Susceptibility but Not for Disease Progression of Geographic Atrophy Due to AMD

BACKGROUND: Age-related macular degeneration (AMD) is a prevalent cause of blindness in Western societies. Variants in the genes encoding complement factor H (CFH), complement component 3 (C3) and age-related maculopathy susceptibility 2 (ARMS2) have repeatedly been shown to confer significant risks...

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Detalles Bibliográficos
Autores principales:	Scholl, Hendrik P. N., Fleckenstein, Monika, Fritsche, Lars G., Schmitz-Valckenberg, Steffen, Göbel, Arno, Adrion, Christine, Herold, Christine, Keilhauer, Claudia N., Mackensen, Friederike, Mößner, Andreas, Pauleikhoff, Daniel, Weinberger, Andreas W. A., Mansmann, Ulrich, Holz, Frank G., Becker, Tim, Weber, Bernhard H. F.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756620/ https://www.ncbi.nlm.nih.gov/pubmed/19823576 http://dx.doi.org/10.1371/journal.pone.0007418

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