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The Epoxygenases CYP2J2 Activates the Nuclear Receptor PPARα In Vitro and In Vivo

BACKGROUND: Peroxisome proliferator-activated receptors (PPARs) are a family of three (PPARα, -β/δ, and -γ) nuclear receptors. In particular, PPARα is involved in regulation of fatty acid metabolism, cell growth and inflammation. PPARα mediates the cardiac fasting response, increasing fatty acid met...

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Detalles Bibliográficos
Autores principales:	Wray, Jessica A., Sugden, Mary C., Zeldin, Darryl C., Greenwood, Gemma K., Samsuddin, Salma, Miller-Degraff, Laura, Bradbury, J. Alyce, Holness, Mark J., Warner, Timothy D., Bishop-Bailey, David
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756622/ https://www.ncbi.nlm.nih.gov/pubmed/19823578 http://dx.doi.org/10.1371/journal.pone.0007421

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