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Ocular Delivery of Compacted DNA-Nanoparticles Does Not Elicit Toxicity in the Mouse Retina

Subretinal delivery of polyethylene glycol-substituted lysine peptide (CK30PEG)-compacted DNA nanoparticles results in efficient gene expression in retinal cells. This work evaluates the ocular safety of compacted DNA nanoparticles. CK30PEG-compacted nanoparticles containing an EGFP expression plasm...

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Detalles Bibliográficos
Autores principales:	Ding, Xi-Qin, Quiambao, Alexander B., Fitzgerald, J. Browning, Cooper, Mark J., Conley, Shannon M., Naash, Muna I.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756629/ https://www.ncbi.nlm.nih.gov/pubmed/19823583 http://dx.doi.org/10.1371/journal.pone.0007410

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