Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Current neural induction protocols in human ES cells (hESCs) rely on embryoid body formation, stromal feeder co-culture, or selective survival conditions; each strategy displaying significant drawbacks such as poorly defined culture conditions, protracted differentiation and low yield. Here we repor...

Descripción completa

Detalles Bibliográficos
Autores principales: Chambers, Stuart M., Fasano, Christopher A., Papapetrou, Eirini P., Tomishima, Mark, Sadelain, Michel, Studer, Lorenz
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756723/
https://www.ncbi.nlm.nih.gov/pubmed/19252484
http://dx.doi.org/10.1038/nbt.1529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2756723/
https://www.ncbi.nlm.nih.gov/pubmed/19252484
http://dx.doi.org/10.1038/nbt.1529

Ejemplares similares