Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding

Coupling between ATPase and track-binding sites is essential for molecular motors to move along cytoskeletal tracks. In dynein, these sites are separated by a long coiled-coil stalk which must mediate communication between them, yet the underlying mechanism remains unclear. Here we show that changes...

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Detalles Bibliográficos
Autores principales: Kon, Takahide, Imamula, Kenji, Roberts, Anthony J., Ohkura, Reiko, Knight, Peter J., Gibbons, I. R., Burgess, Stan A., Sutoh, Kazuo
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757048/
https://www.ncbi.nlm.nih.gov/pubmed/19198589
http://dx.doi.org/10.1038/nsmb.1555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757048/
https://www.ncbi.nlm.nih.gov/pubmed/19198589
http://dx.doi.org/10.1038/nsmb.1555

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