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Helix sliding in the stalk coiled coil of dynein couples ATPase and microtubule binding
Coupling between ATPase and track-binding sites is essential for molecular motors to move along cytoskeletal tracks. In dynein, these sites are separated by a long coiled-coil stalk which must mediate communication between them, yet the underlying mechanism remains unclear. Here we show that changes...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757048/ https://www.ncbi.nlm.nih.gov/pubmed/19198589 http://dx.doi.org/10.1038/nsmb.1555 |