Cargando…

Probing the HIV-1 Genomic RNA Trafficking Pathway and Dimerization by Genetic Recombination and Single Virion Analyses

Once transcribed, the nascent full-length RNA of HIV-1 must travel to the appropriate host cell sites to be translated or to find a partner RNA for copackaging to form newly generated viruses. In this report, we sought to delineate the location where HIV-1 RNA initiates dimerization and the influenc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Moore, Michael D., Nikolaitchik, Olga A., Chen, Jianbo, Hammarskjöld, Marie-Louise, Rekosh, David, Hu, Wei-Shau
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757677/ https://www.ncbi.nlm.nih.gov/pubmed/19834549 http://dx.doi.org/10.1371/journal.ppat.1000627

Ejemplares similares

A Long-Awaited Structure Is Rev-ealed
por: Hammarskjold, Marie-Louise, et al.
Publicado: (2011)

SR proteins: To shuttle or not to shuttle, that is the question
por: Hammarskjold, Marie-Louise, et al.
Publicado: (2017)

Evolutionary conservation of a molecular machinery for export and expression of mRNAs with retained introns
por: Wang, Baomin, et al.
Publicado: (2015)

Rev-Rev Response Element Activity Selection Bias at the HIV Transmission Bottleneck
por: Jackson, Patrick E. H., et al.
Publicado: (2023)

Recombination is required for efficient HIV-1 replication and the maintenance of viral genome integrity
por: Rawson, Jonathan M O, et al.
Publicado: (2018)

Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation
por: Delviks-Frankenberry, Krista A., et al.
Publicado: (2016)

Dimeric RNA Recognition Regulates HIV-1 Genome Packaging
por: Nikolaitchik, Olga A., et al.
Publicado: (2013)

The HIV-1 Rev response element (RRE) adopts alternative conformations that promote different rates of virus replication
por: Sherpa, Chringma, et al.
Publicado: (2015)

Retromer Regulates HIV-1 Envelope Glycoprotein Trafficking and Incorporation into Virions
por: Groppelli, Elisabetta, et al.
Publicado: (2014)

HIV-1 Rev interacts with HERV-K RcREs present in the human genome and promotes export of unspliced HERV-K proviral RNA
por: Gray, Laurie R., et al.
Publicado: (2019)

Mechanisms and Factors that Influence High Frequency Retroviral Recombination
por: Delviks-Frankenberry, Krista, et al.
Publicado: (2011)

HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
por: Dzhivhuho, Godfrey, et al.
Publicado: (2022)

IQGAP1 Negatively Regulates HIV-1 Gag Trafficking and Virion Production
por: Sabo, Yosef, et al.
Publicado: (2020)

Retroviral Env Glycoprotein Trafficking and Incorporation into Virions
por: Murakami, Tsutomu
Publicado: (2012)

Superinfection Exclusion of Alphaherpesviruses Interferes with Virion Trafficking
por: Cwick, James P., et al.
Publicado: (2022)

Rev–Rev Response Element Activity Selection Bias at the Human Immunodeficiency Virus Transmission Bottleneck
por: Jackson, Patrick E H, et al.
Publicado: (2023)

The relationship between HIV-1 genome RNA dimerization, virion maturation and infectivity†
por: Ohishi, Masahisa, et al.
Publicado: (2011)

Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa
por: Matume, Nontokozo D., et al.
Publicado: (2019)

Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution
por: Chen, Jianbo, et al.
Publicado: (2020)

An NXF1 mRNA with a retained intron is expressed in hippocampal and neocortical neurons and is translated into a protein that functions as an Nxf1 cofactor
por: Li, Ying, et al.
Publicado: (2016)

Nef does not contribute to replication differences between R5 pre-AIDS and AIDS HIV-1 clones from patient ACH142
por: Olivieri, Kevin C, et al.
Publicado: (2008)

HIV Virions as Nanoscopic Test Tubes for Probing Oligomerization of the Integrase Enzyme
por: Borrenberghs, Doortje, et al.
Publicado: (2014)

A novel retroviral vector system to analyze expression from mRNA with retained introns using fluorescent proteins and flow cytometry
por: Jackson, Patrick E. H., et al.
Publicado: (2019)

High level of HIV-1 drug resistance mutations in patients with unsuppressed viral loads in rural northern South Africa
por: Etta, Elizabeth M., et al.
Publicado: (2017)

Human endogenous retrovirus-K mRNA expression and genomic alignment data in hepatoblastoma
por: Grabski, David F, et al.
Publicado: (2020)

Plasma Membrane Anchoring and Gag:Gag Multimerization on Viral RNA Are Critical Properties of HIV-1 Gag Required To Mediate Efficient Genome Packaging
por: Duchon, Alice, et al.
Publicado: (2021)

The dimerization domain of HIV-1 viral infectivity factor Vif is required to block virion incorporation of APOBEC3G
por: Miller, James H, et al.
Publicado: (2007)

Morphogenesis of the Infectious HIV-1 Virion
por: Sakuragi, Jun-ichi
Publicado: (2011)

EGFR trafficking: effect of dimerization, dynamics, and mutation
por: Schultz, Destiny F., et al.
Publicado: (2023)

Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
por: Millard, Rebecca S., et al.
Publicado: (2022)

HIV-1 usurps transcription start site heterogeneity of host RNA polymerase II to maximize replication fitness
por: Nikolaitchik, Olga A., et al.
Publicado: (2023)

Development of Lentiviral Vectors for HIV-1 Gene Therapy with Vif-Resistant APOBEC3G
por: Delviks-Frankenberry, Krista A., et al.
Publicado: (2019)

Mechanism of HIV-1 Virion Entrapment by Tetherin
por: Venkatesh, Siddarth, et al.
Publicado: (2013)

RNA and lessons from viruses
por: Hammarskjöld, Marie-Louise
Publicado: (2015)

Dimerization of sortilin regulates its trafficking to extracellular vesicles
por: Itoh, Shinsuke, et al.
Publicado: (2018)

Development of a Cell-Based Luciferase Complementation Assay for Identification of SARS-CoV-2 3CL(pro) Inhibitors
por: Rawson, Jonathan M. O., et al.
Publicado: (2021)

APOBEC3G induces a hypermutation gradient: purifying selection at multiple steps during HIV-1 replication results in levels of G-to-A mutations that are high in DNA, intermediate in cellular viral RNA, and low in virion RNA
por: Russell, Rebecca A, et al.
Publicado: (2009)

Proteomic and Functional Analyses of the Virion Transmembrane Proteome of Cyprinid Herpesvirus 3
por: Vancsok, Catherine, et al.
Publicado: (2017)

Virion stiffness regulates immature HIV-1 entry
por: Pang, Hong-Bo, et al.
Publicado: (2013)

Host Molecule Incorporation into HIV Virions, Potential Influences in HIV Pathogenesis
por: Munoz, Olivia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9h86vpiuvtfm1l9iv3rer62nsg