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EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK–calmodulin interaction
Small conductance calcium-activated potassium (SK) channels respond to intracellular Ca(2+) via constitutively associated calmodulin (CaM). Previous studies have proposed a modular design for the interaction between CaM and SK channels. The C-lobe and the linker of CaM are thought to regulate the co...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757765/ https://www.ncbi.nlm.nih.gov/pubmed/19752189 http://dx.doi.org/10.1085/jgp.200910295 |