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XBP1 governs late events in plasma cell differentiation and is not required for antigen-specific memory B cell development
The unfolded protein response (UPR) is a stress response pathway that is driven by the increased load of unfolded proteins in the endoplasmic reticulum of highly secretory cells such as plasma cells (PCs). X box binding protein 1 (XBP1) is a transcription factor that mediates one branch of the UPR a...
| Autores principales: | , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757870/ https://www.ncbi.nlm.nih.gov/pubmed/19752183 http://dx.doi.org/10.1084/jem.20090738 |