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Crohn's disease adherent-invasive Escherichia coli colonize and induce strong gut inflammation in transgenic mice expressing human CEACAM

Abnormal expression of CEACAM6 is observed at the apical surface of the ileal epithelium in Crohn's disease (CD) patients, and CD ileal lesions are colonized by pathogenic adherent-invasive Escherichia coli (AIEC). We investigated the ability of AIEC reference strain LF82 to colonize the intest...

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Detalles Bibliográficos
Autores principales: Carvalho, Frédéric A., Barnich, Nicolas, Sivignon, Adeline, Darcha, Claude, Chan, Carlos H.F., Stanners, Clifford P., Darfeuille-Michaud, Arlette
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757893/
https://www.ncbi.nlm.nih.gov/pubmed/19737864
http://dx.doi.org/10.1084/jem.20090741