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HCO(3) (−)/Cl(−) Exchange Inactivation and Reactivation during Mouse Oocyte Meiosis Correlates with MEK/MAPK-Regulated Ae2 Plasma Membrane Localization

BACKGROUND: Germinal Vesicle (GV) stage mouse oocytes in first meiotic prophase exhibit highly active HCO(3) (−)/Cl(−) exchange—a class of transport nearly ubiquitously involved in regulation of intracellular pH and cell volume. During meiosis, however, oocyte HCO(3) (−)/Cl(−) exchange becomes inact...

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Detalles Bibliográficos
Autores principales: Zhou, Chenxi, Tiberi, Mario, Liang, Binhui, Alper, Seth L., Baltz, Jay M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757902/
https://www.ncbi.nlm.nih.gov/pubmed/19823673
http://dx.doi.org/10.1371/journal.pone.0007417