Psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of frontal sinus

INTRODUCTION: Psammomatoid ossifying fibroma (POF) is a rare, slowly progressive tumor of the extragnathic craniofacial bones, with a tendency toward locally aggressive behavior. CASE REPORT: The pathognomonic histologic feature is the presence of spherical ossicles, which are similar to psammoma bodies. DISCUSSION: Fibro-osseous lesions composed of POF and aneurysmal bone cyst (ABC) of the frontal sinus in a 12-year-old boy is reported, followed by a literature review. CONCLUSION: To our knowledge, this is the second case of a fibro-osseous lesion composed of ossifying fibroma with reactive ABC to be reported in the literature.