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Staphylococcus aureus α-Hemolysin Activates the NLRP3-Inflammasome in Human and Mouse Monocytic Cells

Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal α-hemolysin is an essential virulence factor in mouse models of CA-MRSA necrotizing pneumonia. S. aureus α-hemolysin has long been known...

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Detalles Bibliográficos
Autores principales:	Craven, Robin R., Gao, Xi, Allen, Irving C., Gris, Denis, Wardenburg, Juliane Bubeck, McElvania-TeKippe, Erin, Ting, Jenny P., Duncan, Joseph A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758589/ https://www.ncbi.nlm.nih.gov/pubmed/19826485 http://dx.doi.org/10.1371/journal.pone.0007446

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