Stem cell transplantation for type 1 diabetes mellitus

BACKGROUND: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration. CONCLUSION: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce co...

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Detalles Bibliográficos
Autores principales: Voltarelli, Júlio C, Couri, Carlos Eduardo Barra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758595/
https://www.ncbi.nlm.nih.gov/pubmed/19825196
http://dx.doi.org/10.1186/1758-5996-1-4
Descripción
Sumario:BACKGROUND: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration. CONCLUSION: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus.

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