Stem cell transplantation for type 1 diabetes mellitus

BACKGROUND: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration. CONCLUSION: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce co...

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Detalles Bibliográficos
Autores principales: Voltarelli, Júlio C, Couri, Carlos Eduardo Barra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758595/
https://www.ncbi.nlm.nih.gov/pubmed/19825196
http://dx.doi.org/10.1186/1758-5996-1-4
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author Voltarelli, Júlio C
Couri, Carlos Eduardo Barra
author_facet Voltarelli, Júlio C
Couri, Carlos Eduardo Barra
author_sort Voltarelli, Júlio C
collection PubMed
description BACKGROUND: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration. CONCLUSION: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus.
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spelling pubmed-27585952009-10-08 Stem cell transplantation for type 1 diabetes mellitus Voltarelli, Júlio C Couri, Carlos Eduardo Barra Diabetol Metab Syndr Review BACKGROUND: The use of stem cells to treat type 1 diabetes mellitus has been proposed for many years, both to downregulate the immune system and to provide β cell regeneration. CONCLUSION: High dose immunosuppression followed by autologous hematopoietic stem cell transplantation is able to induce complete remission (insulin independence) in most patients with early onset type 1 diabetes mellitus. BioMed Central 2009-09-16 /pmc/articles/PMC2758595/ /pubmed/19825196 http://dx.doi.org/10.1186/1758-5996-1-4 Text en Copyright © 2009 Voltarelli and Couri; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( (http://creativecommons.org/licenses/by/2.0) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Voltarelli, Júlio C
Couri, Carlos Eduardo Barra
Stem cell transplantation for type 1 diabetes mellitus
title Stem cell transplantation for type 1 diabetes mellitus
title_full Stem cell transplantation for type 1 diabetes mellitus
title_fullStr Stem cell transplantation for type 1 diabetes mellitus
title_full_unstemmed Stem cell transplantation for type 1 diabetes mellitus
title_short Stem cell transplantation for type 1 diabetes mellitus
title_sort stem cell transplantation for type 1 diabetes mellitus
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758595/
https://www.ncbi.nlm.nih.gov/pubmed/19825196
http://dx.doi.org/10.1186/1758-5996-1-4
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