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Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPase
Meiotic crossovers are produced when programmed double-strand breaks (DSBs) are repaired by recombination from homologous chromosomes (homologues). In a wide variety of organisms, meiotic HORMA-domain proteins are required to direct DSB repair towards homologues. This inter-homologue bias is require...
Autores principales: | Wojtasz, Lukasz, Daniel, Katrin, Roig, Ignasi, Bolcun-Filas, Ewelina, Xu, Huiling, Boonsanay, Verawan, Eckmann, Christian R., Cooke, Howard J., Jasin, Maria, Keeney, Scott, McKay, Michael J., Toth, Attila |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758600/ https://www.ncbi.nlm.nih.gov/pubmed/19851446 http://dx.doi.org/10.1371/journal.pgen.1000702 |
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