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A simple and efficient algorithm for genome-wide homozygosity analysis in disease
Here we propose a simple statistical algorithm for rapidly scoring loci associated with disease or traits due to recessive mutations or deletions using genome-wide single nucleotide polymorphism genotyping case–control data in unrelated individuals. This algorithm identifies loci by defining homozyg...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758715/ https://www.ncbi.nlm.nih.gov/pubmed/19756043 http://dx.doi.org/10.1038/msb.2009.53 |