A Mediator of Rho-dependent Invasion Moonlights as a Methionine Salvage Enzyme

RhoA controls changes in cell morphology and invasion associated with cancer phenotypes. Cell lines derived from melanoma tumors at varying stages revealed that RhoA is selectively activated in cells of metastatic origin. We describe a functional proteomics strategy to identify proteins regulated by...

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Detalles Bibliográficos
Autores principales: Kabuyama, Yukihito, Litman, Elizabeth S., Templeton, Paul D., Metzner, Sandra I., Witze, Eric S., Argast, Gretchen M., Langer, Stephen J., Polvinen, Kirsi, Shellman, Yiqun, Chan, Daniel, Shabb, John B., Fitzpatrick, James E., Resing, Katheryn A., Sousa, Marcelo C., Ahn, Natalie G.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758758/
https://www.ncbi.nlm.nih.gov/pubmed/19620624
http://dx.doi.org/10.1074/mcp.M900178-MCP200

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