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Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region
BACKGROUND: PPE38 (Rv2352c) is a member of the large PPE gene family of Mycobacterium tuberculosis and related mycobacteria. The function of PPE proteins is unknown but evidence suggests that many are cell-surface associated and recognised by the host immune system. Previous studies targeting other...
Autores principales: | McEvoy, Christopher RE, van Helden, Paul D, Warren, Robin M, van Pittius, Nicolaas C Gey |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758852/ https://www.ncbi.nlm.nih.gov/pubmed/19769792 http://dx.doi.org/10.1186/1471-2148-9-237 |
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