Cargando…

In Silico screening for functional candidates amongst hypothetical proteins

BACKGROUND: The definition of a hypothetical protein is a protein that is predicted to be expressed from an open reading frame, but for which there is no experimental evidence of translation. Hypothetical proteins constitute a substantial fraction of proteomes of human as well as of other eukaryotes...

Descripción completa

Detalles Bibliográficos
Autores principales:	Desler, Claus, Suravajhala, Prashanth, Sanderhoff, May, Rasmussen, Merete, Rasmussen, Lene Juel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Methodology Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2758874/ https://www.ncbi.nlm.nih.gov/pubmed/19754976 http://dx.doi.org/10.1186/1471-2105-10-289

Ejemplares similares

The Effect of Mitochondrial Dysfunction on Cytosolic Nucleotide Metabolism
por: Desler, Claus, et al.
Publicado: (2010)

A model to predict the function of hypothetical proteins through a nine-point classification scoring schema
por: Ijaq, Johny, et al.
Publicado: (2019)

The Role of Mitochondrial Dysfunction in the Progression of Alzheimer’s Disease
por: Desler, Claus, et al.
Publicado: (2018)

The Importance of Mitochondrial DNA in Aging and Cancer
por: Desler, Claus, et al.
Publicado: (2011)

Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
por: Bjerregaard, Victoria A., et al.
Publicado: (2020)

Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2015)

From Powerhouse to Perpetrator—Mitochondria in Health and Disease
por: Fakouri, Nima B., et al.
Publicado: (2019)

Correction: Identification of Functional Candidates amongst Hypothetical Proteins of Treponema pallidum ssp. pallidum
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2018)

Hypothetical Proteins as Predecessors of Long Non-coding RNAs
por: Malik, Girik, et al.
Publicado: (2020)

Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage
por: Hopkinson, Branden M., et al.
Publicado: (2017)

Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
por: Desler, Claus, et al.
Publicado: (2012)

A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
por: Syed, Salahuddin, et al.
Publicado: (2016)

Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
por: Desler, Claus, et al.
Publicado: (2015)

In silico screening for candidate chassis strains of free fatty acid-producing cyanobacteria
por: Motwalli, Olaa, et al.
Publicado: (2017)

Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
por: Peeters, Marlies J. W., et al.
Publicado: (2021)

In silico design and screening of hypothetical MOF-74 analogs and their experimental synthesis
por: Witman, Matthew, et al.
Publicado: (2016)

Enterococcus faecalis Infection Causes Inflammation, Intracellular Oxphos-Independent ROS Production, and DNA Damage in Human Gastric Cancer Cells
por: Strickertsson, Jesper A. B., et al.
Publicado: (2013)

In silico structural and functional characterization of hypothetical proteins from Monkeypox virus
por: Gupta, Kajal
Publicado: (2023)

Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells
por: Maynard, Scott, et al.
Publicado: (2013)

Hypothetical in silico model of the early-stage intermediate in protein folding
por: Kalinowska, Barbara, et al.
Publicado: (2013)

Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
por: Subramanian, Veena, et al.
Publicado: (2021)

Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays
por: Heinen, Christopher D, et al.
Publicado: (2012)

In Silico Structural and Functional Annotation of Hypothetical Proteins of Vibrio cholerae O139
por: Islam, Md. Saiful, et al.
Publicado: (2015)

Correction: In silico structural and functional characterization of hypothetical proteins from Monkeypox virus
por: Gupta, Kajal
Publicado: (2023)

Structural and functional characterization of a hypothetical protein in the RD7 region in clinical isolates of Mycobacterium tuberculosis — an in silico approach to candidate vaccines
por: Kootery, Kaviya Parambath, et al.
Publicado: (2022)

In silico molecular cytogenetics: a bioinformatic approach to prioritization of candidate genes and copy number variations for basic and clinical genome research
por: Iourov, Ivan Y, et al.
Publicado: (2014)

In Silico Characterization of Uncharacterized Proteins From Multiple Strains of Clostridium Difficile
por: Abbasi, Bilal Ahmed, et al.
Publicado: (2022)

In silico Functional Annotation and Characterization of Hypothetical Proteins from Serratia marcescens FGI94
por: Prabhu, D., et al.
Publicado: (2020)

In-Silico Functional Annotation of Plasmodium falciparum Hypothetical Proteins to Identify Novel Drug Targets
por: Singh, Gagandeep, et al.
Publicado: (2022)

Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
por: Keijzers, Guido, et al.
Publicado: (2015)

Hypo, hype and ‘hyp’ human proteins
por: Suravajhala, Prashanth
Publicado: (2007)

Statistical dictionaries for hypothetical in silico model of the early-stage intermediate in protein folding
por: Kalinowska, Barbara, et al.
Publicado: (2015)

In silico functional prediction of hypothetical proteins from the core genome of Corynebacterium pseudotuberculosis biovar ovis
por: Araújo, Carlos Leonardo, et al.
Publicado: (2020)

The prevalence of and factors associated with inclusion of non-English language studies in Campbell systematic reviews: a survey and meta-epidemiological study
por: Neimann Rasmussen, Lauge, et al.
Publicado: (2018)

AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
por: Pencheva, Tania, et al.
Publicado: (2008)

Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
por: Lopez-Contreras, Andres J., et al.
Publicado: (2015)

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD(+) precursor nicotinamide riboside
por: Anugula, Sharath, et al.
Publicado: (2023)

Pharmacogenetic testing revisited: 5′ nuclease real-time polymerase chain reaction test panels for genotyping CYP2D6 and CYP2C19
por: Larsen, Jens Borggaard, et al.
Publicado: (2017)

A novel wearable device to deliver unconstrained, unpredictable slip perturbations during gait
por: Rasmussen, Corbin M., et al.
Publicado: (2019)

Screening and characterization of hypothetical proteins of Plasmodium falciparum as novel vaccine candidates in the fight against malaria using reverse vaccinology
por: Aguttu, Claire, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_92orjr2jgd3nmd52hlet32fpht