Proposed Regulation of Gene Expression by Glucose in Rodent Heart

BACKGROUND: During pressure overload-induced hypertrophy, unloading-induced atrophy, and diabetes mellitus, the heart induces ‘fetal’ genes (e.g. myosin heavy chain β; mhcβ). HYPOTHESIS: We propose that altered glucose homeostasis within the cardiomyocyte acts as a central mechanism for the regulati...

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Detalles Bibliográficos
Autores principales: Young, Martin E., Yan, Jie, Razeghi, Peter, Cooksey, Robert C., Guthrie, Patrick H., Stepkowski, Stanislaw M., McClain, Donald A., Tian, Rong, Taegtmeyer, Heinrich
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759127/
https://www.ncbi.nlm.nih.gov/pubmed/19936093

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