A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes

In microarray studies several statistical methods have been proposed with the purpose of identifying differentially expressed genes in two varieties. A commonly used method is an analysis of variance model where only the effect of interaction between variety and gene is tested. In this paper we argu...

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Detalles Bibliográficos
Autores principales: Feten, Guri, Aastveit, Are Halvor, Snipen, Lars, Almøy, Trygve
Formato: Texto
Lenguaje:English
Publicado: Libertas Academica 2007
Materias:
Discussion
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759136/
https://www.ncbi.nlm.nih.gov/pubmed/19936077
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author Feten, Guri
Aastveit, Are Halvor
Snipen, Lars
Almøy, Trygve
author_facet Feten, Guri
Aastveit, Are Halvor
Snipen, Lars
Almøy, Trygve
author_sort Feten, Guri
collection PubMed
description In microarray studies several statistical methods have been proposed with the purpose of identifying differentially expressed genes in two varieties. A commonly used method is an analysis of variance model where only the effect of interaction between variety and gene is tested. In this paper we argue that in addition to the interaction effects, the main effect of variety should simultaneously also be taken into account when posting the hypothesis.
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spelling pubmed-27591362009-11-23 A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes Feten, Guri Aastveit, Are Halvor Snipen, Lars Almøy, Trygve Gene Regul Syst Bio Discussion In microarray studies several statistical methods have been proposed with the purpose of identifying differentially expressed genes in two varieties. A commonly used method is an analysis of variance model where only the effect of interaction between variety and gene is tested. In this paper we argue that in addition to the interaction effects, the main effect of variety should simultaneously also be taken into account when posting the hypothesis. Libertas Academica 2007-06-15 /pmc/articles/PMC2759136/ /pubmed/19936077 Text en © 2007 The authors. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Discussion
Feten, Guri
Aastveit, Are Halvor
Snipen, Lars
Almøy, Trygve
A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title_full A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title_fullStr A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title_full_unstemmed A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title_short A Discussion Concerning the Inclusion of Variety Effect when Analysis of Variance is Used to Detect Differentially Expressed Genes
title_sort discussion concerning the inclusion of variety effect when analysis of variance is used to detect differentially expressed genes
topic Discussion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759136/
https://www.ncbi.nlm.nih.gov/pubmed/19936077
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