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Caspase-Dependent Inhibition of Mousepox Replication by gzmB

BACKGROUND: Ectromelia virus is a natural mouse pathogen, causing mousepox. The cytotoxic T (Tc) cell granule serine-protease, granzyme B, is important for its control, but the underlying mechanism is unknown. Using ex vivo virus immune Tc cells, we have previously shown that granzyme B is able to a...

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Detalles Bibliográficos
Autores principales:	Pardo, Julián, Gálvez, Eva Ma, Koskinen, Aulikki, Simon, Markus M., Lobigs, Mario, Regner, Matthias, Müllbacher, Arno
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759507/ https://www.ncbi.nlm.nih.gov/pubmed/19838298 http://dx.doi.org/10.1371/journal.pone.0007512

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