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DAZL Relieves miRNA-Mediated Repression of Germline mRNAs by Controlling Poly(A) Tail Length in Zebrafish

BACKGROUND: During zebrafish embryogenesis, microRNA (miRNA) miR-430 contributes to restrict Nanos1 and TDRD7 to primordial germ cells (PGCs) by inducing mRNA deadenylation, mRNA degradation, and translational repression of nanos1 and tdrd7 mRNAs in somatic cells. The nanos1 and tdrd7 3′UTRs include...

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Detalles Bibliográficos
Autores principales:	Takeda, Yasuaki, Mishima, Yuichiro, Fujiwara, Toshinobu, Sakamoto, Hiroshi, Inoue, Kunio
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759513/ https://www.ncbi.nlm.nih.gov/pubmed/19838299 http://dx.doi.org/10.1371/journal.pone.0007513

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