Sequence and Structure Signatures of Cancer Mutation Hotspots in Protein Kinases

Protein kinases are the most common protein domains implicated in cancer, where somatically acquired mutations are known to be functionally linked to a variety of cancers. Resequencing studies of protein kinase coding regions have emphasized the importance of sequence and structure determinants of c...

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Detalles Bibliográficos
Autores principales: Dixit, Anshuman, Yi, Lin, Gowthaman, Ragul, Torkamani, Ali, Schork, Nicholas J., Verkhivker, Gennady M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759519/
https://www.ncbi.nlm.nih.gov/pubmed/19834613
http://dx.doi.org/10.1371/journal.pone.0007485

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759519/
https://www.ncbi.nlm.nih.gov/pubmed/19834613
http://dx.doi.org/10.1371/journal.pone.0007485

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