Selection of Inhibitor-Resistant Viral Potassium Channels Identifies a Selectivity Filter Site that Affects Barium and Amantadine Block

BACKGROUND: Understanding the interactions between ion channels and blockers remains an important goal that has implications for delineating the basic mechanisms of ion channel function and for the discovery and development of ion channel directed drugs. METHODOLOGY/PRINCIPAL FINDINGS: We used genet...

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Detalles Bibliográficos
Autores principales: Chatelain, Franck C., Gazzarrini, Sabrina, Fujiwara, Yuichiro, Arrigoni, Cristina, Domigan, Courtney, Ferrara, Giuseppina, Pantoja, Carlos, Thiel, Gerhard, Moroni, Anna, Minor, Daniel L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759520/
https://www.ncbi.nlm.nih.gov/pubmed/19834614
http://dx.doi.org/10.1371/journal.pone.0007496

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