Large A-fiber activity is required for microglial proliferation and p38 MAPK activation in the spinal cord: different effects of resiniferatoxin and bupivacaine on spinal microglial changes after spared nerve injury

BACKGROUND: After peripheral nerve injury, spontaneous ectopic activity arising from the peripheral axons plays an important role in inducing central sensitization and neuropathic pain. Recent evidence indicates that activation of spinal cord microglia also contributes to the development of neuropat...

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Detalles Bibliográficos
Autores principales: Suter, Marc R, Berta, Temugin, Gao, Yong-Jing, Decosterd, Isabelle, Ji, Ru-Rong
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759920/
https://www.ncbi.nlm.nih.gov/pubmed/19772627
http://dx.doi.org/10.1186/1744-8069-5-53

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