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Mutagenesis of the fusion peptide-like domain of hepatitis C virus E1 glycoprotein: involvement in cell fusion and virus entry

BACKGROUND: Envelope (E) glycoprotein E2 of the hepatitis C virus (HCV) mediates binding of the virus to target cell receptors. Nevertheless, the precise role of E1 in viral entry remains elusive. METHODS: To understand the involvement of the fusion peptide-like domain positioned at residues 264 to...

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Detalles Bibliográficos
Autores principales: Li, Hsiao-Fen, Huang, Chia-Hsuan, Ai, Li-Shuang, Chuang, Chin-Kai, Chen, Steve SL
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759930/
https://www.ncbi.nlm.nih.gov/pubmed/19778418
http://dx.doi.org/10.1186/1423-0127-16-89

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