Cargando…

Gene expression profiles associated with aging and mortality in humans

We investigated the hypothesis that gene expression profiles in cultured cell lines from adults, aged 57–97 years, contain information about the biological age and potential longevity of the donors. We studied 104 unrelated grandparents from 31 Utah CEU (Centre d’Etude du Polymorphisme Humain – Utah...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kerber, Richard A, O’Brien, Elizabeth, Cawthon, Richard M
Formato:	Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2009
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2759984/ https://www.ncbi.nlm.nih.gov/pubmed/19245677 http://dx.doi.org/10.1111/j.1474-9726.2009.00467.x

Ejemplares similares

A Genome-Wide Study Replicates Linkage of 3p22-24 to Extreme Longevity in Humans and Identifies Possible Additional Loci
por: Kerber, Richard A., et al.
Publicado: (2012)

Mitochondrial genomic variation associated with higher mitochondrial copy number: the Cache County Study on Memory Health and Aging
por: Ridge, Perry G, et al.
Publicado: (2014)

Mitochondrial Genomic Analysis of Late Onset Alzheimer’s Disease Reveals Protective Haplogroups H6A1A/H6A1B: The Cache County Study on Memory in Aging
por: Ridge, Perry G., et al.
Publicado: (2012)

Germline mutation rates in young adults predict longevity and reproductive lifespan
por: Cawthon, Richard M., et al.
Publicado: (2020)

Hospitalization for pertussis: profiles and case costs by age
por: O'Brien, Judith A, et al.
Publicado: (2005)

Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders
por: Hall, Lynsey S., et al.
Publicado: (2021)

Concordance between Thioacetamide-Induced Liver Injury in Rat and Human In Vitro Gene Expression Data
por: Schyman, Patric, et al.
Publicado: (2020)

Association Between Automotive Assembly Plant Closures and Opioid Overdose Mortality in the United States: A Difference-in-Differences Analysis
por: Venkataramani, Atheendar S., et al.
Publicado: (2019)

Beneficial Effects of Alcohol in Old Age
por: O’Brien, F. H.
Publicado: (1882)

Symptom profiling for infectious intestinal disease (IID): Do symptom profiles alter with age?
por: Donaldson, Anna L., et al.
Publicado: (2022)

Analysis of human sarcospan as a candidate gene for CFEOM1
por: O'Brien, Kristine F, et al.
Publicado: (2001)

Age‐associated microRNA expression in human peripheral blood is associated with all‐cause mortality and age‐related traits
por: Huan, Tianxiao, et al.
Publicado: (2017)

Parental age and gene expression profiles in individual human blastocysts
por: Kawai, Kiyotaka, et al.
Publicado: (2018)

Aging-related changes in the gene expression profile of human lungs
por: Jeong, Ina, et al.
Publicado: (2020)

Is perceived neighbourhood physical disorder associated with muscle strength in middle aged and older men and women? Findings from the US health and retirement study
por: Duchowny, Kate A, et al.
Publicado: (2020)

Sequential Use of Transcriptional Profiling, Expression Quantitative Trait Mapping, and Gene Association Implicates MMP20 in Human Kidney Aging
por: Wheeler, Heather E., et al.
Publicado: (2009)

Genes with human-specific features are primarily involved with brain, immune and metabolic evolution
por: Bitar, Mainá, et al.
Publicado: (2019)

Telomeres, Aging and Exercise: Guilty by Association?
por: Chilton, Warrick, et al.
Publicado: (2017)

Transcriptomic profiling of the human brain reveals that altered synaptic gene expression is associated with chronological aging
por: Dillman, Allissa A., et al.
Publicado: (2017)

Telomere length measurement by a novel monochrome multiplex quantitative PCR method
por: Cawthon, Richard M.
Publicado: (2009)

Sarcopenia and Post-Operative Morbidity and Mortality in Patients with Gastric Cancer
por: O'Brien, Stephen, et al.
Publicado: (2018)

Association of aging with gene expression profiling in mouse submandibular glands
por: Saito, Yoshiro, et al.
Publicado: (2015)

Gene Expression Profiles Associated with Brain Aging are Altered in Schizophrenia
por: Sabunciyan, Sarven
Publicado: (2019)

The rate of leukocyte telomere shortening predicts mortality from cardiovascular disease in elderly men
por: Epel, Elissa S., et al.
Publicado: (2008)

Screening for low testosterone is needed for early identification and treatment of men at high risk of mortality from Covid-19
por: Rowland, Simon Peter, et al.
Publicado: (2020)

Whole-Blood Gene Expression Profiles Associated with Mortality in Community-Acquired Pneumonia
por: Viasus, Diego, et al.
Publicado: (2023)

Gestational age‐dependent gene expression profiling of ATP‐binding cassette transporters in the healthy human placenta
por: Imperio, Guinever E., et al.
Publicado: (2018)

Anti-Aging β-Klotho Gene-Activated Scaffold Promotes Rejuvenative Wound Healing Response in Human Adipose-Derived Stem Cells
por: Laiva, Ashang L., et al.
Publicado: (2021)

Gene expression profiling of human ovarian tumours
por: Biade, S, et al.
Publicado: (2006)

Age-Period-Cohort Models
por: O'Brien, Robert
Publicado: (2014)

Substrate composition and dimensionality direct osteocyte gene expression
por: Dhannoon, Amenah, et al.
Publicado: (2015)

Gene expression profiling of aging reveals activation of a p53-mediated transcriptional program
por: Edwards, Michael G, et al.
Publicado: (2007)

Discrimination between uterine serous papillary carcinomas and ovarian serous papillary tumours by gene expression profiling
por: Santin, A D, et al.
Publicado: (2004)

Stalling life expectancy trends in Europe and decomposition analysis of mortality data
por: Kabir, Z, et al.
Publicado: (2023)

CT-DERIVED PARAVERTEBRAL MUSCLE RADIOMIC FEATURES ARE ASSOCIATED WITH MORTALITY IN THE MROS STUDY
por: Lenchik, Leon, et al.
Publicado: (2022)

Chromosome Missegregation in Single Human Oocytes Is Related to the Age and Gene Expression Profile
por: Barone, Stefano, et al.
Publicado: (2020)

Gene Expression Profiles for the Identification of Prevalent Atrial Fibrillation
por: Thériault, Sébastien, et al.
Publicado: (2017)

Muscular expressions: profiling genes in complex tissues
por: Hampson, Richard, et al.
Publicado: (2001)

Species interactions drive the spread of ampicillin resistance in human-associated gut microbiota
por: O’Brien, Siobhán, et al.
Publicado: (2021)

Identifying gene expression profiles associated with neurogenesis and inflammation in the human subependymal zone from development through aging
por: Bitar, Mainá, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_uq65n1f6tl71rt529pjncbqpnr