DYRK1A, a Novel Determinant of the Methionine-Homocysteine Cycle in Different Mouse Models Overexpressing this Down-Syndrome-Associated Kinase

BACKGROUND: Hyperhomocysteinemia, characterized by increased plasma homocysteine level, is associated with an increased risk of atherosclerosis. On the contrary, patients with Down syndrome appear to be protected from the development of atherosclerosis. We previously found a deleterious effect of hy...

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Detalles Bibliográficos
Autores principales: Noll, Christophe, Planque, Chris, Ripoll, Clémentine, Guedj, Fayçal, Diez, Anna, Ducros, Véronique, Belin, Nicole, Duchon, Arnaud, Paul, Jean-Louis, Badel, Anne, de Freminville, Bénédicte, Grattau, Yann, Bléhaut, Henri, Herault, Yann, Janel, Nathalie, Delabar, Jean-Maurice
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760102/
https://www.ncbi.nlm.nih.gov/pubmed/19844572
http://dx.doi.org/10.1371/journal.pone.0007540

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