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Progressive GAA·TTC Repeat Expansion in Human Cell Lines

Trinucleotide repeat expansion is the genetic basis for a sizeable group of inherited neurological and neuromuscular disorders. Friedreich ataxia (FRDA) is a relentlessly progressive neurodegenerative disorder caused by GAA·TTC repeat expansion in the first intron of the FXN gene. The expanded repea...

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Detalles Bibliográficos
Autores principales:	Ditch, Scott, Sammarco, Mimi C., Banerjee, Ayan, Grabczyk, Ed
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760145/ https://www.ncbi.nlm.nih.gov/pubmed/19876374 http://dx.doi.org/10.1371/journal.pgen.1000704

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