Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance

The evolution of drug resistance is an important process that affects clinical outcomes. Resistance to fluconazole, the most widely used antifungal, is often associated with acquired aneuploidy. Here we provide a longitudinal study of the prevalence and dynamics of gross chromosomal rearrangements,...

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Detalles Bibliográficos
Autores principales: Selmecki, Anna M., Dulmage, Keely, Cowen, Leah E., Anderson, James B., Berman, Judith
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760147/
https://www.ncbi.nlm.nih.gov/pubmed/19876375
http://dx.doi.org/10.1371/journal.pgen.1000705

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760147/
https://www.ncbi.nlm.nih.gov/pubmed/19876375
http://dx.doi.org/10.1371/journal.pgen.1000705

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