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Acquisition of Aneuploidy Provides Increased Fitness during the Evolution of Antifungal Drug Resistance
The evolution of drug resistance is an important process that affects clinical outcomes. Resistance to fluconazole, the most widely used antifungal, is often associated with acquired aneuploidy. Here we provide a longitudinal study of the prevalence and dynamics of gross chromosomal rearrangements,...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760147/ https://www.ncbi.nlm.nih.gov/pubmed/19876375 http://dx.doi.org/10.1371/journal.pgen.1000705 |