Secondary Amyloidosis Associated with Multiple Sclerosis

BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a...

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Detalles Bibliográficos
Autores principales: Kang, Seok Jae, Yi, Joo-Hark, Hong, Hyun-Seok, Jang, Si-Hyung, Park, Moon-Hyang, Kim, Ho-Jung, Lee, Kyu-Yong, Lee, Young-Joo, Han, Sang-Woong, Koh, Seong-Ho
Formato: Texto
Lenguaje:English
Publicado: Korean Neurological Association 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760720/
https://www.ncbi.nlm.nih.gov/pubmed/19826566
http://dx.doi.org/10.3988/jcn.2009.5.3.146
Descripción
Sumario:BACKGROUND: Multiple sclerosis (MS) is a demyelinating disease of the central nervous system. Secondary amyloidosis can occur as a complication of chronic systemic inflammatory and infectious diseases. Until now there has been no report of secondary amyloidosis associated with MS. We report herein a case of renal biopsy-proven secondary amyloidosis in a patient with MS. CASE REPORT: A 41-year-old woman with MS was hospitalized due to aggravated quadriparesis and edema in both lower extremities. Laboratory findings showed nephrotic-range proteinuria and hypoalbuminemia. A percutaneous renal biopsy procedure was performed, the results of which revealed secondary amyloid-A-type amyloidosis associated with MS. CONCLUSIONS: This is the first report of secondary amyloidosis associated with MS.

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