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Intracellular Serotonin Modulates Insulin Secretion from Pancreatic β-Cells by Protein Serotonylation

While serotonin (5-HT) co-localization with insulin in granules of pancreatic β-cells was demonstrated more than three decades ago, its physiological role in the etiology of diabetes is still unclear. We combined biochemical and electrophysiological analyses of mice selectively deficient in peripher...

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Detalles Bibliográficos
Autores principales: Paulmann, Nils, Grohmann, Maik, Voigt, Jörg-Peter, Bert, Bettina, Vowinckel, Jakob, Bader, Michael, Skelin, Maša, Jevšek, Marko, Fink, Heidrun, Rupnik, Marjan, Walther, Diego J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760755/
https://www.ncbi.nlm.nih.gov/pubmed/19859528
http://dx.doi.org/10.1371/journal.pbio.1000229

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