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In vitro characterization of a miR-122-sensitive double-helical switch element in the 5′ region of hepatitis C virus RNA
It has been proposed that the hepatitis C virus (HCV) internal ribosome entry site (IRES) resides within a locked conformation, owing to annealing of its immediate flanking sequences. In this study, structure probing using Escherichia coli dsRNA-specific RNase III and other classical tools showed th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760801/ https://www.ncbi.nlm.nih.gov/pubmed/19578061 http://dx.doi.org/10.1093/nar/gkp553 |