Discovering ligands for a microRNA precursor with peptoid microarrays

We have screened peptoid microarrays to identify specific ligands for the RNA hairpin precursor of miR-21, a microRNA involved in cancer and heart disease. Microarrays were printed by spotting a library of 7680 N-substituted oligoglycines (peptoids) onto glass slides. Two compounds on the array spec...

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Detalles Bibliográficos
Autores principales: Chirayil, Sara, Chirayil, Rachel, Luebke, Kevin J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760809/
https://www.ncbi.nlm.nih.gov/pubmed/19561197
http://dx.doi.org/10.1093/nar/gkp549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760809/
https://www.ncbi.nlm.nih.gov/pubmed/19561197
http://dx.doi.org/10.1093/nar/gkp549

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