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Discovering ligands for a microRNA precursor with peptoid microarrays
We have screened peptoid microarrays to identify specific ligands for the RNA hairpin precursor of miR-21, a microRNA involved in cancer and heart disease. Microarrays were printed by spotting a library of 7680 N-substituted oligoglycines (peptoids) onto glass slides. Two compounds on the array spec...
Autores principales: | Chirayil, Sara, Chirayil, Rachel, Luebke, Kevin J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760809/ https://www.ncbi.nlm.nih.gov/pubmed/19561197 http://dx.doi.org/10.1093/nar/gkp549 |
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