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Large-scale assignment of orthology: back to phylogenetics?

Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for g...

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Detalles Bibliográficos
Autor principal: Gabaldón, Toni
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760865/
https://www.ncbi.nlm.nih.gov/pubmed/18983710
http://dx.doi.org/10.1186/gb-2008-9-10-235
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author Gabaldón, Toni
author_facet Gabaldón, Toni
author_sort Gabaldón, Toni
collection PubMed
description Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies.
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spelling pubmed-27608652009-10-30 Large-scale assignment of orthology: back to phylogenetics? Gabaldón, Toni Genome Biol Review Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies. BioMed Central 2008 2008-10-30 /pmc/articles/PMC2760865/ /pubmed/18983710 http://dx.doi.org/10.1186/gb-2008-9-10-235 Text en Copyright © 2008 BioMed Central Ltd
spellingShingle Review
Gabaldón, Toni
Large-scale assignment of orthology: back to phylogenetics?
title Large-scale assignment of orthology: back to phylogenetics?
title_full Large-scale assignment of orthology: back to phylogenetics?
title_fullStr Large-scale assignment of orthology: back to phylogenetics?
title_full_unstemmed Large-scale assignment of orthology: back to phylogenetics?
title_short Large-scale assignment of orthology: back to phylogenetics?
title_sort large-scale assignment of orthology: back to phylogenetics?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760865/
https://www.ncbi.nlm.nih.gov/pubmed/18983710
http://dx.doi.org/10.1186/gb-2008-9-10-235
work_keys_str_mv AT gabaldontoni largescaleassignmentoforthologybacktophylogenetics