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Large-scale assignment of orthology: back to phylogenetics?
Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for g...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760865/ https://www.ncbi.nlm.nih.gov/pubmed/18983710 http://dx.doi.org/10.1186/gb-2008-9-10-235 |
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author | Gabaldón, Toni |
author_facet | Gabaldón, Toni |
author_sort | Gabaldón, Toni |
collection | PubMed |
description | Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies. |
format | Text |
id | pubmed-2760865 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27608652009-10-30 Large-scale assignment of orthology: back to phylogenetics? Gabaldón, Toni Genome Biol Review Reliable orthology prediction is central to comparative genomics. Although orthology is defined by phylogenetic criteria, most automated prediction methods are based on pairwise sequence comparisons. Recently, automated phylogeny-based orthology prediction has emerged as a feasible alternative for genome-wide studies. BioMed Central 2008 2008-10-30 /pmc/articles/PMC2760865/ /pubmed/18983710 http://dx.doi.org/10.1186/gb-2008-9-10-235 Text en Copyright © 2008 BioMed Central Ltd |
spellingShingle | Review Gabaldón, Toni Large-scale assignment of orthology: back to phylogenetics? |
title | Large-scale assignment of orthology: back to phylogenetics? |
title_full | Large-scale assignment of orthology: back to phylogenetics? |
title_fullStr | Large-scale assignment of orthology: back to phylogenetics? |
title_full_unstemmed | Large-scale assignment of orthology: back to phylogenetics? |
title_short | Large-scale assignment of orthology: back to phylogenetics? |
title_sort | large-scale assignment of orthology: back to phylogenetics? |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760865/ https://www.ncbi.nlm.nih.gov/pubmed/18983710 http://dx.doi.org/10.1186/gb-2008-9-10-235 |
work_keys_str_mv | AT gabaldontoni largescaleassignmentoforthologybacktophylogenetics |