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Tools for simulating evolution of aligned genomic regions with integrated parameter estimation
Controlled simulations of genome evolution are useful for benchmarking tools. However, many simulators lack extensibility and cannot measure parameters directly from data. These issues are addressed by three new open-source programs: GSIMULATOR (for neutrally evolving DNA), SIMGRAM (for generic stru...
Autores principales: | Varadarajan, Avinash, Bradley, Robert K, Holmes, Ian H |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2760874/ https://www.ncbi.nlm.nih.gov/pubmed/18840304 http://dx.doi.org/10.1186/gb-2008-9-10-r147 |
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