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The pol3-t Hyperrecombination Phenotype and DNA Damage-Induced Recombination in Saccharomyces cerevisiae Is RAD50 Dependent

The DNA polymerase δ (POL3/CDC2) allele pol3-t of Saccharomyces cerevisiae has previously been shown to be sensitive to methylmethanesulfonate (MMS) and has been proposed to be involved in base excision repair. Our results, however, show that the pol3-t mutation is synergistic for MMS sensitivity wi...

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Detalles Bibliográficos
Autores principales: Galli, Alvaro, Hafer, Kurt, Cervelli, Tiziana, Schiestl, Robert H.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761004/
https://www.ncbi.nlm.nih.gov/pubmed/19834566
http://dx.doi.org/10.1155/2009/312710