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Hematopoietic stem cells depend upon G(s)α-mediated signalling to engraft bone marrow
Hematopoietic stem/progenitor cells (HSPC) transition in location during development1 and circulate in mammals throughout life2, moving into and out of the bloodstream to engage bone marrow (BM) niches in sequential steps of homing, engraftment and retention3–5. We show here that HSPC engraftment of...
Autores principales: | Adams, Gregor B., Alley, Ian R., Chung, Ung-il, Chabner, Karissa T., Jeanson, Nathaniel T., Lo Celso, Cristina, Marsters, Emily S., Chen, Min, Weinstein, Lee S., Lin, Charles P., Kronenberg, Henry M., Scadden, David T. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761017/ https://www.ncbi.nlm.nih.gov/pubmed/19322176 http://dx.doi.org/10.1038/nature07859 |
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