Severe toxicity of skin rash, fever and diarrhea associated with imatinib: case report and review of skin toxicities associated with tyrosine kinase inhibitors

Chronic myeloid leukemia (CML) is characterized by a Philadelphia chromosome which contains an oncogene, bcr-abl. This oncogene encodes a tyrosine kinase which is constitutively activated. Imatinib, a tyrosine kinase inhibitor (TKI), has been widely used in the treatment of CML. Dasatinib and niloti...

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Detalles Bibliográficos
Autores principales: Huang, Xuan, Patel, Samir, Ahmed, Nasir, Seiter, Karen, Liu, Delong
Formato: Texto
Lenguaje:English
Publicado: Dove Medical Press 2009
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761170/
https://www.ncbi.nlm.nih.gov/pubmed/19920908

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