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Ascorbic acid and tetrahydrobiopterin potentiate the EDHF phenomenon by generating hydrogen peroxide
AIMS: Our objective was to investigate whether pro-oxidant properties of ascorbic acid (AA) and tetrahydrobiopterin (BH(4)) modulate endothelium-dependent, electrotonically mediated arterial relaxation. METHODS AND RESULTS: In studies with rabbit iliac artery (RIA) rings, NO-independent, endothelium...
Autores principales: | Garry, Ambroise, Edwards, David H., Fallis, Ian F., Jenkins, Robert L., Griffith, Tudor M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761203/ https://www.ncbi.nlm.nih.gov/pubmed/19592567 http://dx.doi.org/10.1093/cvr/cvp235 |
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