Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF

microRNA-155 (miR-155) has been implicated as a central regulator of the immune system, but its function during acute inflammatory responses is still poorly understood. Here we show that exposure of cultured macrophages and mice to lipopolysaccharide (LPS) leads to up-regulation of miR-155 and that...

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Detalles Bibliográficos
Autores principales: Worm, Jesper, Stenvang, Jan, Petri, Andreas, Frederiksen, Klaus Stensgaard, Obad, Susanna, Elmén, Joacim, Hedtjärn, Maj, Straarup, Ellen Marie, Hansen, Jens Bo, Kauppinen, Sakari
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761263/
https://www.ncbi.nlm.nih.gov/pubmed/19596814
http://dx.doi.org/10.1093/nar/gkp577

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