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Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response

ATM and ATR protein kinases play a crucial role in cellular DNA damage responses. The inhibition of ATM and ATR can lead to the abolition of the function of cell cycle checkpoints. In this regard, it is expected that checkpoint inhibitors can serve as sensitizing agents for anti-cancer chemo/radioth...

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Detalles Bibliográficos
Autores principales:	Nishida, Hiroshi, Tatewaki, Naoto, Nakajima, Yuki, Magara, Taku, Ko, Kam Ming, Hamamori, Yasuo, Konishi, Tetsuya
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761266/ https://www.ncbi.nlm.nih.gov/pubmed/19625493 http://dx.doi.org/10.1093/nar/gkp593

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