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The PKR-binding domain of adenovirus VA RNA(I) exists as a mixture of two functionally non-equivalent structures

VA RNA(I) is a non-coding adenoviral transcript that counteracts the host cell anti-viral defenses such as immune responses mediated via PKR. We investigated potential alternate secondary structure conformations within the PKR-binding domain of VA RNA(I) using site-directed mutagenesis, RNA UV-melti...

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Detalles Bibliográficos
Autores principales:	Wahid, Ahmed M., Coventry, Veronica K., Conn, Graeme L.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761268/ https://www.ncbi.nlm.nih.gov/pubmed/19635730 http://dx.doi.org/10.1093/nar/gkp595

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