Repair of gaps opposite lesions by homologous recombination in mammalian cells

Damages in the DNA template inhibit the progression of replication, which may cause single-stranded gaps. Such situations can be tolerated by translesion DNA synthesis (TLS), or by homology-dependent repair (HDR), which is based on transfer or copying of the missing information from the replicated s...

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Detalles Bibliográficos
Autores principales: Adar, Sheera, Izhar, Lior, Hendel, Ayal, Geacintov, Nicholas, Livneh, Zvi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761288/
https://www.ncbi.nlm.nih.gov/pubmed/19654238
http://dx.doi.org/10.1093/nar/gkp632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761288/
https://www.ncbi.nlm.nih.gov/pubmed/19654238
http://dx.doi.org/10.1093/nar/gkp632

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