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Repair of gaps opposite lesions by homologous recombination in mammalian cells
Damages in the DNA template inhibit the progression of replication, which may cause single-stranded gaps. Such situations can be tolerated by translesion DNA synthesis (TLS), or by homology-dependent repair (HDR), which is based on transfer or copying of the missing information from the replicated s...
Autores principales: | Adar, Sheera, Izhar, Lior, Hendel, Ayal, Geacintov, Nicholas, Livneh, Zvi |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761288/ https://www.ncbi.nlm.nih.gov/pubmed/19654238 http://dx.doi.org/10.1093/nar/gkp632 |
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