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The rapamycin-regulated gene expression signature determines prognosis for breast cancer

BACKGROUND: Mammalian target of rapamycin (mTOR) is a serine/threonine kinase involved in multiple intracellular signaling pathways promoting tumor growth. mTOR is aberrantly activated in a significant portion of breast cancers and is a promising target for treatment. Rapamycin and its analogues are...

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Detalles Bibliográficos
Autores principales: Akcakanat, Argun, Zhang, Li, Tsavachidis, Spiridon, Meric-Bernstam, Funda
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2761377/
https://www.ncbi.nlm.nih.gov/pubmed/19778445
http://dx.doi.org/10.1186/1476-4598-8-75